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Acute NADPH oxidase activation potentiates cerebrovascular permeability response to bradykinin in ischemia–reperfusion

Free radical generation is a key event in cerebral reperfusion injury. Bradykinin (Bk) and interleukin-1β (IL-1β) have both been implicated in edema formation after stroke, although acute Bk application itself results in only a modest permeability increase. We have investigated the molecular mechani...

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Detalles Bibliográficos
Autores principales: Woodfin, Abigail, Hu, De-En, Sarker, Mosharraf, Kurokawa, Tsuyoshi, Fraser, Paul
Formato: Texto
Lenguaje:English
Publicado: Elsevier Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3038265/
https://www.ncbi.nlm.nih.gov/pubmed/21167936
http://dx.doi.org/10.1016/j.freeradbiomed.2010.12.010

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