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Chromosome 11q13.5 variant associated with childhood eczema: An effect supplementary to filaggrin mutations

BACKGROUND: Atopic eczema is a common inflammatory skin disease with multifactorial etiology. The genetic basis is incompletely understood; however, loss of function mutations in the filaggrin gene (FLG) are the most significant and widely replicated genetic risk factor reported to date. The first g...

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Detalles Bibliográficos
Autores principales: O'Regan, Gráinne M., Campbell, Linda E., Cordell, Heather J., Irvine, Alan D., McLean, W.H. Irwin, Brown, Sara J.
Formato: Texto
Lenguaje:English
Publicado: Mosby 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3038266/
https://www.ncbi.nlm.nih.gov/pubmed/20109745
http://dx.doi.org/10.1016/j.jaci.2009.10.046

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