Cargando…
Chromosome 11q13.5 variant associated with childhood eczema: An effect supplementary to filaggrin mutations
BACKGROUND: Atopic eczema is a common inflammatory skin disease with multifactorial etiology. The genetic basis is incompletely understood; however, loss of function mutations in the filaggrin gene (FLG) are the most significant and widely replicated genetic risk factor reported to date. The first g...
Autores principales: | O'Regan, Gráinne M., Campbell, Linda E., Cordell, Heather J., Irvine, Alan D., McLean, W.H. Irwin, Brown, Sara J. |
---|---|
Formato: | Texto |
Lenguaje: | English |
Publicado: |
Mosby
2010
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3038266/ https://www.ncbi.nlm.nih.gov/pubmed/20109745 http://dx.doi.org/10.1016/j.jaci.2009.10.046 |
Ejemplares similares
-
Filaggrin-stratified transcriptomic analysis of pediatric skin identifies mechanistic pathways in patients with atopic dermatitis
por: Cole, Christian, et al.
Publicado: (2014) -
Raman profiles of the stratum corneum define 3 filaggrin genotype–determined atopic dermatitis endophenotypes
por: O'Regan, Gráinne M., et al.
Publicado: (2010) -
Filaggrin loss-of-function mutations are associated with enhanced expression of IL-1 cytokines in the stratum corneum of patients with atopic dermatitis and in a murine model of filaggrin deficiency
por: Kezic, Sanja, et al.
Publicado: (2012) -
Filaggrin breakdown products determine corneocyte conformation in patients with atopic dermatitis
por: Riethmuller, Christoph, et al.
Publicado: (2015) -
Filaggrin-null mutations are associated with increased maturation markers on Langerhans cells
por: Leitch, Claire S., et al.
Publicado: (2016)