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The peptide hormone ghrelin binds to membrane-mimetics via its octanoyl chain and an adjacent phenylalanine
The peptide hormone ghrelin, which is the natural ligand of the membrane-bound growth hormone secretagogue receptor (GHS-R), regulates overall body and cell growth, energy homeostasis, carbohydrate, protein and lipid metabolism and water electrolyte balance. It contains an O-acyl linked octanoyl gro...
Autores principales: | , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Elsevier Science
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3038380/ https://www.ncbi.nlm.nih.gov/pubmed/20621491 http://dx.doi.org/10.1016/j.bmc.2010.06.062 |