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The peptide hormone ghrelin binds to membrane-mimetics via its octanoyl chain and an adjacent phenylalanine

The peptide hormone ghrelin, which is the natural ligand of the membrane-bound growth hormone secretagogue receptor (GHS-R), regulates overall body and cell growth, energy homeostasis, carbohydrate, protein and lipid metabolism and water electrolyte balance. It contains an O-acyl linked octanoyl gro...

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Detalles Bibliográficos
Autores principales: Großauer, Jörg, Kosol, Simone, Schrank, Evelyne, Zangger, Klaus
Formato: Texto
Lenguaje:English
Publicado: Elsevier Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3038380/
https://www.ncbi.nlm.nih.gov/pubmed/20621491
http://dx.doi.org/10.1016/j.bmc.2010.06.062