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The Dam1 ring binds to the E-hook of tubulin and diffuses along the microtubule
There has been much effort in recent years aimed at understanding the molecular mechanism by which the Dam1 kinetochore complex is able to couple microtubule depolymerization to poleward movement. Both a biased diffusion and a forced walk model have been proposed, and several key functional aspects...
Autores principales: | Ramey, Vincent H., Wang, Hong-Wei, Nakajima, Yuko, Wong, Amanda, Liu, Jian, Drubin, David, Barnes, Georjana, Nogales, Eva |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The American Society for Cell Biology
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3038644/ https://www.ncbi.nlm.nih.gov/pubmed/21169562 http://dx.doi.org/10.1091/mbc.E10-10-0841 |
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