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Using Nuclear Receptor Activity to Stratify Hepatocarcinogens

BACKGROUND: Nuclear receptors (NR) are a superfamily of ligand-activated transcription factors that control a range of cellular processes. Persistent stimulation of some NR is a non-genotoxic mechanism of rodent liver cancer with unclear relevance to humans. Here we report on a systematic analysis o...

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Detalles Bibliográficos
Autores principales:	Shah, Imran, Houck, Keith, Judson, Richard S., Kavlock, Robert J., Martin, Matthew T., Reif, David M., Wambaugh, John, Dix, David J.
Formato:	Texto
Lenguaje:	English
Publicado:	Public Library of Science 2011
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3038857/ https://www.ncbi.nlm.nih.gov/pubmed/21339822 http://dx.doi.org/10.1371/journal.pone.0014584

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