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Xenotransplantation of Mitochondrial Electron Transfer Enzyme, Ndi1, in Myocardial Reperfusion Injury
A significant consequence of ischemia/reperfusion (I/R) is mitochondrial respiratory dysfunction, leading to energetic deficits and cellular toxicity from reactive oxygen species (ROS). Mammalian complex I, a NADH-quinone oxidoreductase enzyme, is a multiple subunit enzyme that oxidizes NADH and pum...
Autores principales: | Perry, Cynthia N., Huang, Chengqun, Liu, Wayne, Magee, Najib, Sousa Carreira, Raquel, Gottlieb, Roberta A. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3038860/ https://www.ncbi.nlm.nih.gov/pubmed/21339825 http://dx.doi.org/10.1371/journal.pone.0016288 |
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