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Reduced spiral ganglion neuronal loss by adjunctive neurotrophin-3 in experimental pneumococcal meningitis
BACKGROUND: Hearing loss is a frequent long-term complication of pneumococcal meningitis (PM). Its main pathological correlate is damage to the organ of Corti and loss of spiral ganglion neurons. The only current treatment option is cochlear implants which require surviving neurons. Here, we investi...
Autores principales: | Demel, Cornelia, Hoegen, Tobias, Giese, Armin, Angele, Barbara, Pfister, Hans-Walter, Koedel, Uwe, Klein, Matthias |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3038911/ https://www.ncbi.nlm.nih.gov/pubmed/21261959 http://dx.doi.org/10.1186/1742-2094-8-7 |
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