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Error and Error Mitigation in Low-Coverage Genome Assemblies
The recent release of twenty-two new genome sequences has dramatically increased the data available for mammalian comparative genomics, but twenty of these new sequences are currently limited to ∼2× coverage. Here we examine the extent of sequencing error in these 2× assemblies, and its potential im...
| Autores principales: | , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2011
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3038916/ https://www.ncbi.nlm.nih.gov/pubmed/21340033 http://dx.doi.org/10.1371/journal.pone.0017034 |