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Low CD4+ T Cell Counts among African HIV-1 Infected Subjects with Group B KIR Haplotypes in the Absence of Specific Inhibitory KIR Ligands

Natural killer (NK) cells are regulated by interactions between polymorphic killer immunoglobulin-like receptors (KIR) and human leukocyte antigens (HLA). Genotypic combinations of KIR3DS1/L1 and HLA Bw4-80I were previously shown to influence HIV-1 disease progression, however other KIR genes have n...

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Detalles Bibliográficos
Autores principales: Jennes, Wim, Verheyden, Sonja, Demanet, Christian, Menten, Joris, Vuylsteke, Bea, Nkengasong, John N., Kestens, Luc
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3038936/
https://www.ncbi.nlm.nih.gov/pubmed/21347267
http://dx.doi.org/10.1371/journal.pone.0017043