Role of innate signalling pathways in the immunogenicity of alphaviral replicon-based vaccines

BACKGROUND: Alphaviral replicon-based vectors induce potent immune responses both when given as viral particles (VREP) or as DNA (DREP). It has been suggested that the strong immune stimulatory effect induced by these types of vectors is mediated by induction of danger signals and activation of inna...

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Detalles Bibliográficos
Autores principales: Näslund, Tanja I, Kostic, Linda, Nordström, Eva KL, Chen, Margaret, Liljeström, Peter
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3038947/
https://www.ncbi.nlm.nih.gov/pubmed/21261958
http://dx.doi.org/10.1186/1743-422X-8-36

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3038947/
https://www.ncbi.nlm.nih.gov/pubmed/21261958
http://dx.doi.org/10.1186/1743-422X-8-36

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