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Role of innate signalling pathways in the immunogenicity of alphaviral replicon-based vaccines
BACKGROUND: Alphaviral replicon-based vectors induce potent immune responses both when given as viral particles (VREP) or as DNA (DREP). It has been suggested that the strong immune stimulatory effect induced by these types of vectors is mediated by induction of danger signals and activation of inna...
| Autores principales: | , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2011
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3038947/ https://www.ncbi.nlm.nih.gov/pubmed/21261958 http://dx.doi.org/10.1186/1743-422X-8-36 |