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Phase I Dose Escalation Study of Sodium Stibogluconate (SSG), a Protein Tyrosine Phosphatase Inhibitor, Combined with Interferon Alpha for Patients with Solid Tumors
Purpose: Sodium stibogluconate (SSG), a small molecule inhibitor of protein tyrosine phosphatases, combined with IFN-alpha-2b (IFN-α) inhibited solid tumor cell line growth in vitro. We conducted a phase I clinical trial with SSG plus IFN-α in advanced cancer patients to assess tolerance, maximum to...
Autores principales: | Naing, Aung, Reuben, James M., Camacho, Luis H., Gao, Hui, Lee, Bang-Ning, Cohen, Evan N., Verschraegen, Claire, Stephen, Saneese, Aaron, Joann, Hong, David, Wheler, Jennifer, Kurzrock, Razelle |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Ivyspring International Publisher
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3039225/ https://www.ncbi.nlm.nih.gov/pubmed/21326629 |
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