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Class II Phosphoinositide 3-Kinase Regulates Exocytosis of Insulin Granules in Pancreatic β Cells

Phosphoinositide 3-kinases (PI3Ks) are critical regulators of pancreatic β cell mass and survival, whereas their involvement in insulin secretion is more controversial. Furthermore, of the different PI3Ks, the class II isoforms were detected in β cells, although their role is still not well understo...

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Detalles Bibliográficos
Autores principales:	Dominguez, Veronica, Raimondi, Claudio, Somanath, Sangeeta, Bugliani, Marco, Loder, Merewyn K., Edling, Charlotte E., Divecha, Nullin, da Silva-Xavier, Gabriela, Marselli, Lorella, Persaud, Shanta J., Turner, Mark D., Rutter, Guy A., Marchetti, Piero, Falasca, Marco, Maffucci, Tania
Formato:	Texto
Lenguaje:	English
Publicado:	American Society for Biochemistry and Molecular Biology 2011
Materias:	Signal Transduction
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3039383/ https://www.ncbi.nlm.nih.gov/pubmed/21127054 http://dx.doi.org/10.1074/jbc.M110.200295

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