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Identification of New Substrates of the Protein-tyrosine Phosphatase PTP1B by Bayesian Integration of Proteome Evidence

There is growing evidence that tyrosine phosphatases display an intrinsic enzymatic preference for the sequence context flanking the target phosphotyrosines. On the other hand, substrate selection in vivo is decisively guided by the enzyme-substrate connectivity in the protein interaction network. W...

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Detalles Bibliográficos
Autores principales:	Ferrari, Emanuela, Tinti, Michele, Costa, Stefano, Corallino, Salvatore, Nardozza, Aurelio Pio, Chatraryamontri, Andrew, Ceol, Arnaud, Cesareni, Gianni, Castagnoli, Luisa
Formato:	Texto
Lenguaje:	English
Publicado:	American Society for Biochemistry and Molecular Biology 2011
Materias:	Genomics and Proteomics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3039405/ https://www.ncbi.nlm.nih.gov/pubmed/21123182 http://dx.doi.org/10.1074/jbc.M110.157420

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