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Functional and structural analyses of N-acylsulfonamide-linked dinucleoside inhibitors of RNase A

Molecular probes are useful for both studying and controlling the functions of enzymes and other proteins. The most useful probes have high affinity for their target, along with small size and resistance to degradation. Here, we report on new surrogates for nucleic acids that fulfill these criteria....

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Detalles Bibliográficos
Autores principales: Thiyagarajan, Nethaji, Smith, Bryan D, Raines, Ronald T, Acharya, K Ravi
Formato: Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3039443/
https://www.ncbi.nlm.nih.gov/pubmed/21205197
http://dx.doi.org/10.1111/j.1742-4658.2010.07976.x