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Functional and structural analyses of N-acylsulfonamide-linked dinucleoside inhibitors of RNase A
Molecular probes are useful for both studying and controlling the functions of enzymes and other proteins. The most useful probes have high affinity for their target, along with small size and resistance to degradation. Here, we report on new surrogates for nucleic acids that fulfill these criteria....
Autores principales: | Thiyagarajan, Nethaji, Smith, Bryan D, Raines, Ronald T, Acharya, K Ravi |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Blackwell Publishing Ltd
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3039443/ https://www.ncbi.nlm.nih.gov/pubmed/21205197 http://dx.doi.org/10.1111/j.1742-4658.2010.07976.x |
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