Cytotoxic Terpene Quinones from Marine Sponges

The 1,4-benzoquinone moiety is a common structural feature in a large number of compounds that have received considerable attention owing to their broad spectrum of biological activities. The cytotoxic and antiproliferative properties of many natural sesquiterpene quinones and hydroquinones from spo...

Descripción completa

Detalles Bibliográficos
Autor principal: Gordaliza, Marina
Formato: Texto
Lenguaje:English
Publicado: Molecular Diversity Preservation International 2010
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3039459/
https://www.ncbi.nlm.nih.gov/pubmed/21339953
http://dx.doi.org/10.3390/md8122849
_version_ 1782198185709535232
author Gordaliza, Marina
author_facet Gordaliza, Marina
author_sort Gordaliza, Marina
collection PubMed
description The 1,4-benzoquinone moiety is a common structural feature in a large number of compounds that have received considerable attention owing to their broad spectrum of biological activities. The cytotoxic and antiproliferative properties of many natural sesquiterpene quinones and hydroquinones from sponges of the order Dictyoceratida, such as avarol, avarone, illimaquinone, nakijiquinone and bolinaquinone, offer promising opportunities for the development of new antitumor agents. The present review summarizes the structure and cytotoxicity of natural terpenequinones/hydroquinones and their bioactive analogues and derivatives.
format Text
id pubmed-3039459
institution National Center for Biotechnology Information
language English
publishDate 2010
publisher Molecular Diversity Preservation International
record_format MEDLINE/PubMed
spelling pubmed-30394592011-02-18 Cytotoxic Terpene Quinones from Marine Sponges Gordaliza, Marina Mar Drugs Review The 1,4-benzoquinone moiety is a common structural feature in a large number of compounds that have received considerable attention owing to their broad spectrum of biological activities. The cytotoxic and antiproliferative properties of many natural sesquiterpene quinones and hydroquinones from sponges of the order Dictyoceratida, such as avarol, avarone, illimaquinone, nakijiquinone and bolinaquinone, offer promising opportunities for the development of new antitumor agents. The present review summarizes the structure and cytotoxicity of natural terpenequinones/hydroquinones and their bioactive analogues and derivatives. Molecular Diversity Preservation International 2010-11-24 /pmc/articles/PMC3039459/ /pubmed/21339953 http://dx.doi.org/10.3390/md8122849 Text en © 2010 by the authors; licensee Molecular Diversity Preservation International, Basel, Switzerland http://creativecommons.org/licenses/by/3.0 This article is an open-access article distributed under the terms and conditions of the Creative Commons Attribution license (http://creativecommons.org/licenses/by/3.0/).
spellingShingle Review
Gordaliza, Marina
Cytotoxic Terpene Quinones from Marine Sponges
title Cytotoxic Terpene Quinones from Marine Sponges
title_full Cytotoxic Terpene Quinones from Marine Sponges
title_fullStr Cytotoxic Terpene Quinones from Marine Sponges
title_full_unstemmed Cytotoxic Terpene Quinones from Marine Sponges
title_short Cytotoxic Terpene Quinones from Marine Sponges
title_sort cytotoxic terpene quinones from marine sponges
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3039459/
https://www.ncbi.nlm.nih.gov/pubmed/21339953
http://dx.doi.org/10.3390/md8122849
work_keys_str_mv AT gordalizamarina cytotoxicterpenequinonesfrommarinesponges

Ejemplares similares