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Mesenteric lymph node cells from neonates present a prominent IL-12 response to CpG oligodeoxynucleotide via an IL-15 feedback loop of amplification
At birth, the immune system is still in development making neonates more susceptible to infections. The recognition of microbial ligands is a key step in the initiation of immune responses. It can be mimicked to stimulate the immune system by the use of synthetic ligands recognising pattern recognit...
Autores principales: | Ferret-Bernard, Stéphanie, Lacroix-Lamandé, Sonia, Remot, Aude, Metton, Coralie, Bernardet, Nelly, Charley, Bernard, Drouet, Françoise, Laurent, Fabrice |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3039596/ https://www.ncbi.nlm.nih.gov/pubmed/21314903 http://dx.doi.org/10.1186/1297-9716-42-19 |
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