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Self-Organization and Regulation of Intrinsically Disordered Proteins with Folded N-Termini

How do mostly disordered proteins coordinate the specific assembly of very large signal transduction protein complexes? A newly emerging hypothesis may provide some clues towards a molecular mechanism.

Detalles Bibliográficos
Autores principales: Simister, Philip C., Schaper, Fred, O'Reilly, Nicola, McGowan, Simon, Feller, Stephan M.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3039663/
https://www.ncbi.nlm.nih.gov/pubmed/21347241
http://dx.doi.org/10.1371/journal.pbio.1000591
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author Simister, Philip C.
Schaper, Fred
O'Reilly, Nicola
McGowan, Simon
Feller, Stephan M.
author_facet Simister, Philip C.
Schaper, Fred
O'Reilly, Nicola
McGowan, Simon
Feller, Stephan M.
author_sort Simister, Philip C.
collection PubMed
description How do mostly disordered proteins coordinate the specific assembly of very large signal transduction protein complexes? A newly emerging hypothesis may provide some clues towards a molecular mechanism.
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spelling pubmed-30396632011-02-23 Self-Organization and Regulation of Intrinsically Disordered Proteins with Folded N-Termini Simister, Philip C. Schaper, Fred O'Reilly, Nicola McGowan, Simon Feller, Stephan M. PLoS Biol Essay How do mostly disordered proteins coordinate the specific assembly of very large signal transduction protein complexes? A newly emerging hypothesis may provide some clues towards a molecular mechanism. Public Library of Science 2011-02-15 /pmc/articles/PMC3039663/ /pubmed/21347241 http://dx.doi.org/10.1371/journal.pbio.1000591 Text en Simister et al. http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.
spellingShingle Essay
Simister, Philip C.
Schaper, Fred
O'Reilly, Nicola
McGowan, Simon
Feller, Stephan M.
Self-Organization and Regulation of Intrinsically Disordered Proteins with Folded N-Termini
title Self-Organization and Regulation of Intrinsically Disordered Proteins with Folded N-Termini
title_full Self-Organization and Regulation of Intrinsically Disordered Proteins with Folded N-Termini
title_fullStr Self-Organization and Regulation of Intrinsically Disordered Proteins with Folded N-Termini
title_full_unstemmed Self-Organization and Regulation of Intrinsically Disordered Proteins with Folded N-Termini
title_short Self-Organization and Regulation of Intrinsically Disordered Proteins with Folded N-Termini
title_sort self-organization and regulation of intrinsically disordered proteins with folded n-termini
topic Essay
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3039663/
https://www.ncbi.nlm.nih.gov/pubmed/21347241
http://dx.doi.org/10.1371/journal.pbio.1000591
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