Cargando…
Break-Induced Replication Is Highly Inaccurate
DNA must be synthesized for purposes of genome duplication and DNA repair. While the former is a highly accurate process, short-patch synthesis associated with repair of DNA damage is often error-prone. Break-induced replication (BIR) is a unique cellular process that mimics normal DNA replication i...
Autores principales: | Deem, Angela, Keszthelyi, Andrea, Blackgrove, Tiffany, Vayl, Alexandra, Coffey, Barbara, Mathur, Ruchi, Chabes, Andrei, Malkova, Anna |
---|---|
Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2011
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3039667/ https://www.ncbi.nlm.nih.gov/pubmed/21347245 http://dx.doi.org/10.1371/journal.pbio.1000594 |
Ejemplares similares
-
Cascades of Genetic Instability Resulting from Compromised Break-Induced Replication
por: Vasan, Soumini, et al.
Publicado: (2014) -
Migrating bubble during break-induced replication drives conservative DNA synthesis
por: Saini, Natalie, et al.
Publicado: (2013) -
Break-Induced Replication and Genome Stability
por: Sakofsky, Cynthia J., et al.
Publicado: (2012) -
The mutation spectrum in genomic late replication domains shapes mammalian GC content
por: Kenigsberg, Ephraim, et al.
Publicado: (2016) -
Microhomology Directs Diverse DNA Break Repair Pathways and Chromosomal Translocations
por: Villarreal, Diana D., et al.
Publicado: (2012)