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Oocyte–Targeted Deletion Reveals That Hsp90b1 Is Needed for the Completion of First Mitosis in Mouse Zygotes

BACKGROUND: Hsp90b1 is an endoplasmic reticulum (ER) chaperone (also named Grp94, ERp99, gp96,Targ2, Tra-1, Tra1, Hspc4) (MGI:98817) contributing with Hspa5 (also named Grp78, BIP) (MGI:95835) to protein folding in ER compartment. Besides its high protein expression in mouse oocytes, little is known...

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Detalles Bibliográficos
Autores principales: Audouard, Christophe, Le Masson, Florent, Charry, Colette, Li, Zihai, Christians, Elisabeth S.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3039677/
https://www.ncbi.nlm.nih.gov/pubmed/21358806
http://dx.doi.org/10.1371/journal.pone.0017109