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Association between C reactive protein and coronary heart disease: mendelian randomisation analysis based on individual participant data

Objective To use genetic variants as unconfounded proxies of C reactive protein concentration to study its causal role in coronary heart disease. Design Mendelian randomisation meta-analysis of individual participant data from 47 epidemiological studies in 15 countries. Participants 194 418 particip...

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Detalles Bibliográficos
Formato: Texto
Lenguaje:English
Publicado: BMJ Publishing Group Ltd. 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3039696/
https://www.ncbi.nlm.nih.gov/pubmed/21325005
http://dx.doi.org/10.1136/bmj.d548