Childhood leukaemia, nuclear sites, and population mixing

The excess of childhood leukaemia (CL) in Seascale, near the Sellafield nuclear reprocessing site in rural NW England, suggested that an epidemic of an underlying infection, to which CL is a rare response, is promoted by marked population mixing (PM) in rural areas, in which the prevalence of suscep...

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Autor principal: Kinlen, L
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2011
Materias:
Minireview
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3039801/
https://www.ncbi.nlm.nih.gov/pubmed/21063418
http://dx.doi.org/10.1038/sj.bjc.6605982
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author Kinlen, L
author_facet Kinlen, L
author_sort Kinlen, L
collection PubMed
description The excess of childhood leukaemia (CL) in Seascale, near the Sellafield nuclear reprocessing site in rural NW England, suggested that an epidemic of an underlying infection, to which CL is a rare response, is promoted by marked population mixing (PM) in rural areas, in which the prevalence of susceptibles is higher than average. This hypothesis has been confirmed by 12 studies in non-radiation situations. Of the five established CL excesses near nuclear sites, four are associated with significant PM; in the fifth, the Krummel power station in Germany, the subject has not been thoroughly investigated.
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spelling pubmed-30398012012-01-04 Childhood leukaemia, nuclear sites, and population mixing Kinlen, L Br J Cancer Minireview The excess of childhood leukaemia (CL) in Seascale, near the Sellafield nuclear reprocessing site in rural NW England, suggested that an epidemic of an underlying infection, to which CL is a rare response, is promoted by marked population mixing (PM) in rural areas, in which the prevalence of susceptibles is higher than average. This hypothesis has been confirmed by 12 studies in non-radiation situations. Of the five established CL excesses near nuclear sites, four are associated with significant PM; in the fifth, the Krummel power station in Germany, the subject has not been thoroughly investigated. Nature Publishing Group 2011-01-04 2010-11-09 /pmc/articles/PMC3039801/ /pubmed/21063418 http://dx.doi.org/10.1038/sj.bjc.6605982 Text en Copyright © 2011 Cancer Research UK https://creativecommons.org/licenses/by/4.0/This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material.If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit https://creativecommons.org/licenses/by/4.0/.
spellingShingle Minireview
Kinlen, L
Childhood leukaemia, nuclear sites, and population mixing
title Childhood leukaemia, nuclear sites, and population mixing
title_full Childhood leukaemia, nuclear sites, and population mixing
title_fullStr Childhood leukaemia, nuclear sites, and population mixing
title_full_unstemmed Childhood leukaemia, nuclear sites, and population mixing
title_short Childhood leukaemia, nuclear sites, and population mixing
title_sort childhood leukaemia, nuclear sites, and population mixing
topic Minireview
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3039801/
https://www.ncbi.nlm.nih.gov/pubmed/21063418
http://dx.doi.org/10.1038/sj.bjc.6605982
work_keys_str_mv AT kinlenl childhoodleukaemianuclearsitesandpopulationmixing

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