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Leptin pro-angiogenic signature in breast cancer is linked to IL-1 signalling

BACKGROUND: Leptin and interleukin-1 (IL-1) upregulate vascular endothelial growth factor (VEGF), promote angiogenesis and are related to worse prognosis of breast cancer. However, it is unknown whether leptin regulates IL-1, and whether these effects are related to leptin-induction of VEGF/VEGFR2 i...

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Detalles Bibliográficos
Autores principales:	Zhou, W, Guo, S, Gonzalez-Perez, R R
Formato:	Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2011
Materias:	Molecular Diagnostics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3039812/ https://www.ncbi.nlm.nih.gov/pubmed/21139583 http://dx.doi.org/10.1038/sj.bjc.6606013

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