Hand pattern indicates prostate cancer risk

BACKGROUND: The ratio of digit lengths is fixed in utero, and may be a proxy indicator for prenatal testosterone levels. METHODS: We analysed the right-hand pattern and prostate cancer risk in 1524 prostate cancer cases and 3044 population-based controls. RESULTS: Compared with index finger shorter...

Descripción completa

Detalles Bibliográficos
Autores principales: Rahman, A A, Lophatananon, A, Stewart-Brown, S, Harriss, D, Anderson, J, Parker, T, Easton, D, Kote-Jarai, Z, Pocock, R, Dearnaley, D, Guy, M, O'Brien, L, Wilkinson, R A, Hall, A L, Sawyer, E, Page, E, Liu, J-F, Eeles, R A, Muir, K
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2011
Materias:
Short Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3039824/
https://www.ncbi.nlm.nih.gov/pubmed/21119657
http://dx.doi.org/10.1038/sj.bjc.6605986
Descripción
Sumario:BACKGROUND: The ratio of digit lengths is fixed in utero, and may be a proxy indicator for prenatal testosterone levels. METHODS: We analysed the right-hand pattern and prostate cancer risk in 1524 prostate cancer cases and 3044 population-based controls. RESULTS: Compared with index finger shorter than ring finger (low 2D : 4D), men with index finger longer than ring finger (high 2D : 4D) showed a negative association, suggesting a protective effect with a 33% risk reduction (odds ratio (OR) 0.67, 95% confidence interval (CI) 0.57–0.80). Risk reduction was even greater (87%) in age group <60 (OR 0.13, 95% CI 0.09–0.21). CONCLUSION: Pattern of finger lengths may be a simple marker of prostate cancer risk, with length of 2D greater than 4D suggestive of lower risk.

Ejemplares similares