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Hand pattern indicates prostate cancer risk
BACKGROUND: The ratio of digit lengths is fixed in utero, and may be a proxy indicator for prenatal testosterone levels. METHODS: We analysed the right-hand pattern and prostate cancer risk in 1524 prostate cancer cases and 3044 population-based controls. RESULTS: Compared with index finger shorter...
| Autores principales: | , , , , , , , , , , , , , , , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group
2011
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3039824/ https://www.ncbi.nlm.nih.gov/pubmed/21119657 http://dx.doi.org/10.1038/sj.bjc.6605986 |
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| author | Rahman, A A Lophatananon, A Stewart-Brown, S Harriss, D Anderson, J Parker, T Easton, D Kote-Jarai, Z Pocock, R Dearnaley, D Guy, M O'Brien, L Wilkinson, R A Hall, A L Sawyer, E Page, E Liu, J-F Eeles, R A Muir, K |
| author_facet | Rahman, A A Lophatananon, A Stewart-Brown, S Harriss, D Anderson, J Parker, T Easton, D Kote-Jarai, Z Pocock, R Dearnaley, D Guy, M O'Brien, L Wilkinson, R A Hall, A L Sawyer, E Page, E Liu, J-F Eeles, R A Muir, K |
| author_sort | Rahman, A A |
| collection | PubMed |
| description | BACKGROUND: The ratio of digit lengths is fixed in utero, and may be a proxy indicator for prenatal testosterone levels. METHODS: We analysed the right-hand pattern and prostate cancer risk in 1524 prostate cancer cases and 3044 population-based controls. RESULTS: Compared with index finger shorter than ring finger (low 2D : 4D), men with index finger longer than ring finger (high 2D : 4D) showed a negative association, suggesting a protective effect with a 33% risk reduction (odds ratio (OR) 0.67, 95% confidence interval (CI) 0.57–0.80). Risk reduction was even greater (87%) in age group <60 (OR 0.13, 95% CI 0.09–0.21). CONCLUSION: Pattern of finger lengths may be a simple marker of prostate cancer risk, with length of 2D greater than 4D suggestive of lower risk. |
| format | Text |
| id | pubmed-3039824 |
| institution | National Center for Biotechnology Information |
| language | English |
| publishDate | 2011 |
| publisher | Nature Publishing Group |
| record_format | MEDLINE/PubMed |
| spelling | pubmed-30398242012-01-04 Hand pattern indicates prostate cancer risk Rahman, A A Lophatananon, A Stewart-Brown, S Harriss, D Anderson, J Parker, T Easton, D Kote-Jarai, Z Pocock, R Dearnaley, D Guy, M O'Brien, L Wilkinson, R A Hall, A L Sawyer, E Page, E Liu, J-F Eeles, R A Muir, K Br J Cancer Short Communication BACKGROUND: The ratio of digit lengths is fixed in utero, and may be a proxy indicator for prenatal testosterone levels. METHODS: We analysed the right-hand pattern and prostate cancer risk in 1524 prostate cancer cases and 3044 population-based controls. RESULTS: Compared with index finger shorter than ring finger (low 2D : 4D), men with index finger longer than ring finger (high 2D : 4D) showed a negative association, suggesting a protective effect with a 33% risk reduction (odds ratio (OR) 0.67, 95% confidence interval (CI) 0.57–0.80). Risk reduction was even greater (87%) in age group <60 (OR 0.13, 95% CI 0.09–0.21). CONCLUSION: Pattern of finger lengths may be a simple marker of prostate cancer risk, with length of 2D greater than 4D suggestive of lower risk. Nature Publishing Group 2011-01-04 2010-11-30 /pmc/articles/PMC3039824/ /pubmed/21119657 http://dx.doi.org/10.1038/sj.bjc.6605986 Text en Copyright © 2011 Cancer Research UK https://creativecommons.org/licenses/by/4.0/This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material.If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit https://creativecommons.org/licenses/by/4.0/. |
| spellingShingle | Short Communication Rahman, A A Lophatananon, A Stewart-Brown, S Harriss, D Anderson, J Parker, T Easton, D Kote-Jarai, Z Pocock, R Dearnaley, D Guy, M O'Brien, L Wilkinson, R A Hall, A L Sawyer, E Page, E Liu, J-F Eeles, R A Muir, K Hand pattern indicates prostate cancer risk |
| title | Hand pattern indicates prostate cancer risk |
| title_full | Hand pattern indicates prostate cancer risk |
| title_fullStr | Hand pattern indicates prostate cancer risk |
| title_full_unstemmed | Hand pattern indicates prostate cancer risk |
| title_short | Hand pattern indicates prostate cancer risk |
| title_sort | hand pattern indicates prostate cancer risk |
| topic | Short Communication |
| url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3039824/ https://www.ncbi.nlm.nih.gov/pubmed/21119657 http://dx.doi.org/10.1038/sj.bjc.6605986 |
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