MEK–ERK-dependent multiple caspase activation by mitochondrial proapoptotic Bcl-2 family proteins is essential for heavy ion irradiation-induced glioma cell death

Recently developed heavy ion irradiation therapy using a carbon beam (CB) against systemic malignancy has numerous advantages. However, the clinical results of CB therapy against glioblastoma still have room for improvement. Therefore, we tried to clarify the molecular mechanism of CB-induced glioma...

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Detalles Bibliográficos
Autores principales: Tomiyama, A, Tachibana, K, Suzuki, K, Seino, S, Sunayama, J, Matsuda, K-i, Sato, A, Matsumoto, Y, Nomiya, T, Nemoto, K, Yamashita, H, Kayama, T, Ando, K, Kitanaka, C
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2010
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3039836/
https://www.ncbi.nlm.nih.gov/pubmed/21364665
http://dx.doi.org/10.1038/cddis.2010.37

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