Growth differentiation factor 15 deficiency protects against atherosclerosis by attenuating CCR2-mediated macrophage chemotaxis

Growth differentiation factor (GDF) 15 is a member of the transforming growth factor β (TGF-β) superfamily, which operates in acute phase responses through a currently unknown receptor. Elevated GDF-15 serum levels were recently identified as a risk factor for acute coronary syndromes. We show that...

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Detalles Bibliográficos
Autores principales: de Jager, Saskia C.A., Bermúdez, Beatriz, Bot, Ilze, Koenen, Rory R., Bot, Martine, Kavelaars, Annemieke, de Waard, Vivian, Heijnen, Cobi J., Muriana, Francisco J.G., Weber, Christian, van Berkel, Theo J.C., Kuiper, Johan, Lee, Se-Jin, Abia, Rocio, Biessen, Erik A.L.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2011
Materias:
Brief Definitive Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3039852/
https://www.ncbi.nlm.nih.gov/pubmed/21242297
http://dx.doi.org/10.1084/jem.20100370

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