Bone marrow CD169(+) macrophages promote the retention of hematopoietic stem and progenitor cells in the mesenchymal stem cell niche

Hematopoietic stem cells (HSCs) reside in specialized bone marrow (BM) niches regulated by the sympathetic nervous system (SNS). Here, we have examined whether mononuclear phagocytes modulate the HSC niche. We defined three populations of BM mononuclear phagocytes that include Gr-1(hi) monocytes (MO...

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Detalles Bibliográficos
Autores principales: Chow, Andrew, Lucas, Daniel, Hidalgo, Andrés, Méndez-Ferrer, Simón, Hashimoto, Daigo, Scheiermann, Christoph, Battista, Michela, Leboeuf, Marylene, Prophete, Colette, van Rooijen, Nico, Tanaka, Masato, Merad, Miriam, Frenette, Paul S.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2011
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3039855/
https://www.ncbi.nlm.nih.gov/pubmed/21282381
http://dx.doi.org/10.1084/jem.20101688

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