Phospholipases A(1)

Phospholipase A(1) (PLA(1)) is an enzyme that hydrolyzes phospholipids and produces 2-acyl-lysophospholipids and fatty acids. This lipolytic activity is conserved in a wide range of organisms but is carried out by a diverse set of PLA(1) enzymes. Where their function is known, PLA(1)s have been show...

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Detalles Bibliográficos
Autores principales: Richmond, Gregory S., Smith, Terry K.
Formato: Texto
Lenguaje:English
Publicado: Molecular Diversity Preservation International (MDPI) 2011
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3039968/
https://www.ncbi.nlm.nih.gov/pubmed/21340002
http://dx.doi.org/10.3390/ijms12010588
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author Richmond, Gregory S.
Smith, Terry K.
author_facet Richmond, Gregory S.
Smith, Terry K.
author_sort Richmond, Gregory S.
collection PubMed
description Phospholipase A(1) (PLA(1)) is an enzyme that hydrolyzes phospholipids and produces 2-acyl-lysophospholipids and fatty acids. This lipolytic activity is conserved in a wide range of organisms but is carried out by a diverse set of PLA(1) enzymes. Where their function is known, PLA(1)s have been shown to act as digestive enzymes, possess central roles in membrane maintenance and remodeling, or regulate important cellular mechanisms by the production of various lysophospholipid mediators, such as lysophosphatidylserine and lysophosphatidic acid, which in turn have multiple biological functions.
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spelling pubmed-30399682011-02-18 Phospholipases A(1) Richmond, Gregory S. Smith, Terry K. Int J Mol Sci Review Phospholipase A(1) (PLA(1)) is an enzyme that hydrolyzes phospholipids and produces 2-acyl-lysophospholipids and fatty acids. This lipolytic activity is conserved in a wide range of organisms but is carried out by a diverse set of PLA(1) enzymes. Where their function is known, PLA(1)s have been shown to act as digestive enzymes, possess central roles in membrane maintenance and remodeling, or regulate important cellular mechanisms by the production of various lysophospholipid mediators, such as lysophosphatidylserine and lysophosphatidic acid, which in turn have multiple biological functions. Molecular Diversity Preservation International (MDPI) 2011-01-18 /pmc/articles/PMC3039968/ /pubmed/21340002 http://dx.doi.org/10.3390/ijms12010588 Text en © 2011 by the authors; licensee Molecular Diversity Preservation International, Basel, Switzerland. http://creativecommons.org/licenses/by/3.0 This article is an open-access article distributed under the terms and conditions of the Creative Commons Attribution license (http://creativecommons.org/licenses/by/3.0/).
spellingShingle Review
Richmond, Gregory S.
Smith, Terry K.
Phospholipases A(1)
title Phospholipases A(1)
title_full Phospholipases A(1)
title_fullStr Phospholipases A(1)
title_full_unstemmed Phospholipases A(1)
title_short Phospholipases A(1)
title_sort phospholipases a(1)
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3039968/
https://www.ncbi.nlm.nih.gov/pubmed/21340002
http://dx.doi.org/10.3390/ijms12010588
work_keys_str_mv AT richmondgregorys phospholipasesa1
AT smithterryk phospholipasesa1

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