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xFITOM: a generic GUI tool to search for transcription factor binding sites
Locating transcription factor binding sites in genomic sequences is a key step in deciphering transcription networks. Currently available software for site search is mostly server-based, limiting the range and flexibility of this type of analysis. xFITOM is a fully customizable program for locating...
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Formato: | Texto |
Lenguaje: | English |
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Biomedical Informatics
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3039987/ https://www.ncbi.nlm.nih.gov/pubmed/21346861 |
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author | Bhargava, Nidhi Erill, Ivan |
author_facet | Bhargava, Nidhi Erill, Ivan |
author_sort | Bhargava, Nidhi |
collection | PubMed |
description | Locating transcription factor binding sites in genomic sequences is a key step in deciphering transcription networks. Currently available software for site search is mostly server-based, limiting the range and flexibility of this type of analysis. xFITOM is a fully customizable program for locating binding sites in genomic sequences written in C++. Through an easy-to-use interface, xFITOM that allows users an unprecedented degree of flexibility in site search. Among other features,it enables users to define motifs by mixing real sites and IUPAC consensus sequences,to search the annotated sequences of unfinished genomes and to choose among 11 different search algorithms. AVAILABILITY: xFITOM is available for download at: http://research.umbc.edu/˜erill |
format | Text |
id | pubmed-3039987 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2010 |
publisher | Biomedical Informatics |
record_format | MEDLINE/PubMed |
spelling | pubmed-30399872011-02-23 xFITOM: a generic GUI tool to search for transcription factor binding sites Bhargava, Nidhi Erill, Ivan Bioinformation Software Locating transcription factor binding sites in genomic sequences is a key step in deciphering transcription networks. Currently available software for site search is mostly server-based, limiting the range and flexibility of this type of analysis. xFITOM is a fully customizable program for locating binding sites in genomic sequences written in C++. Through an easy-to-use interface, xFITOM that allows users an unprecedented degree of flexibility in site search. Among other features,it enables users to define motifs by mixing real sites and IUPAC consensus sequences,to search the annotated sequences of unfinished genomes and to choose among 11 different search algorithms. AVAILABILITY: xFITOM is available for download at: http://research.umbc.edu/˜erill Biomedical Informatics 2010-07-06 /pmc/articles/PMC3039987/ /pubmed/21346861 Text en © 2010 Biomedical Informatics This is an open-access article, which permits unrestricted use, distribution, and reproduction in any medium, for non-commercial purposes, provided the original author and source are credited. |
spellingShingle | Software Bhargava, Nidhi Erill, Ivan xFITOM: a generic GUI tool to search for transcription factor binding sites |
title | xFITOM: a generic GUI tool to search for transcription factor binding sites |
title_full | xFITOM: a generic GUI tool to search for transcription factor binding sites |
title_fullStr | xFITOM: a generic GUI tool to search for transcription factor binding sites |
title_full_unstemmed | xFITOM: a generic GUI tool to search for transcription factor binding sites |
title_short | xFITOM: a generic GUI tool to search for transcription factor binding sites |
title_sort | xfitom: a generic gui tool to search for transcription factor binding sites |
topic | Software |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3039987/ https://www.ncbi.nlm.nih.gov/pubmed/21346861 |
work_keys_str_mv | AT bhargavanidhi xfitomagenericguitooltosearchfortranscriptionfactorbindingsites AT erillivan xfitomagenericguitooltosearchfortranscriptionfactorbindingsites |