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Modeling RNA interference in mammalian cells

BACKGROUND: RNA interference (RNAi) is a regulatory cellular process that controls post-transcriptional gene silencing. During RNAi double-stranded RNA (dsRNA) induces sequence-specific degradation of homologous mRNA via the generation of smaller dsRNA oligomers of length between 21-23nt (siRNAs). s...

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Detalles Bibliográficos
Autores principales:	Cuccato, Giulia, Polynikis, Athanasios, Siciliano, Velia, Graziano, Mafalda, di Bernardo, Mario, di Bernardo, Diego
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2011
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3040133/ https://www.ncbi.nlm.nih.gov/pubmed/21272352 http://dx.doi.org/10.1186/1752-0509-5-19

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