Comparing the effect of hydroxyethyl starch 130/0.4 with balanced crystalloid solution on mortality and kidney failure in patients with severe sepsis (6S - Scandinavian Starch for Severe Sepsis/Septic Shock trial): Study protocol, design and rationale for a double-blinded, randomised clinical trial

BACKGROUND: By tradition colloid solutions have been used to obtain fast circulatory stabilisation in shock, but high molecular weight hydroxyethyl starch (HES) may cause acute kidney failure in patients with severe sepsis. Now lower molecular weight HES 130/0.4 is the preferred colloid in Scandinav...

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Detalles Bibliográficos
Autores principales: Perner, Anders, Haase, Nicolai, Wetterslev, Jørn, Åneman, Anders, Tenhunen, Jyrki, Guttormsen, Anne Berit, Klemenzson, Gudmundur, Pott, Frank, Bødker, Karen Doris, Bådstøløkken, Per Martin, Bendtsen, Asger, Søe-Jensen, Peter, Tousi, Hamid, Bestle, Morten, Pawlowicz, Malgorzata, Winding, Robert, Bülow, Hans-Henrik, Kancir, Claude, Steensen, Morten, Nielsen, Jonas, Fogh, Bjarne, Madsen, Kristian R, Larsen, Nils H, Carlsson, Marcela, Wiis, Jørgen, Petersen, John Asger, Iversen, Susanne, Schøidt, Ole, Leivdal, Siv, Berezowicz, Pawel, Pettilä, Ville, Ruokonen, Esko, Klepstad, Pål, Karlsson, Sari, Kaukonen, Maija, Rutanen, Juha, Karason, Sigurbergur, Kjældgaard, Anne Lene, Holst, Lars Broksø, Wernerman, Jan
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Study Protocol
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3040153/
https://www.ncbi.nlm.nih.gov/pubmed/21269526
http://dx.doi.org/10.1186/1745-6215-12-24

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