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Ubiquitinylation of α-Synuclein by Carboxyl Terminus Hsp70-Interacting Protein (CHIP) Is Regulated by Bcl-2-Associated Athanogene 5 (BAG5)
Parkinson's disease (PD) is a common neurodegenerative condition in which abnormalities in protein homeostasis, or proteostasis, may lead to accumulation of the protein α-synuclein (α-syn). Mutations within or multiplications of the gene encoding α-syn are known to cause genetic forms of PD and...
Autores principales: | Kalia, Lorraine V., Kalia, Suneil K., Chau, Hien, Lozano, Andres M., Hyman, Bradley T., McLean, Pamela J. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3040167/ https://www.ncbi.nlm.nih.gov/pubmed/21358815 http://dx.doi.org/10.1371/journal.pone.0014695 |
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