Cargando…

Ubiquitinylation of α-Synuclein by Carboxyl Terminus Hsp70-Interacting Protein (CHIP) Is Regulated by Bcl-2-Associated Athanogene 5 (BAG5)

Parkinson's disease (PD) is a common neurodegenerative condition in which abnormalities in protein homeostasis, or proteostasis, may lead to accumulation of the protein α-synuclein (α-syn). Mutations within or multiplications of the gene encoding α-syn are known to cause genetic forms of PD and...

Descripción completa

Detalles Bibliográficos
Autores principales:	Kalia, Lorraine V., Kalia, Suneil K., Chau, Hien, Lozano, Andres M., Hyman, Bradley T., McLean, Pamela J.
Formato:	Texto
Lenguaje:	English
Publicado:	Public Library of Science 2011
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3040167/ https://www.ncbi.nlm.nih.gov/pubmed/21358815 http://dx.doi.org/10.1371/journal.pone.0014695

Ejemplares similares

Regulation of Parkin-dependent mitophagy by Bcl-2-associated athanogene (BAG) family members
por: Kapadia, Minesh, et al.
Publicado: (2020)

Bcl-2-associated athanogene 5 (BAG5) regulates Parkin-dependent mitophagy and cell death
por: De Snoo, Mitchell L., et al.
Publicado: (2019)

C-terminus of Hsp70 Interacting Protein (CHIP) and Neurodegeneration: Lessons from the Bench and Bedside
por: Mylvaganam, Sivakami, et al.
Publicado: (2021)

BAG5 Promotes Alpha-Synuclein Oligomer Formation and Functionally Interacts With the Autophagy Adaptor Protein p62
por: Friesen, Erik L., et al.
Publicado: (2020)

Bcl-2 associated athanogene 5 (Bag5) is overexpressed in prostate cancer and inhibits ER-stress induced apoptosis
por: Bruchmann, Anja, et al.
Publicado: (2013)

Regulation of osteoblast development by Bcl-2-associated athanogene-1 (BAG-1)
por: Greenhough, Joanna, et al.
Publicado: (2016)

Origin and Evolution of the Human Bcl2-Associated Athanogene-1 (BAG-1)
por: Nguyen, Peter, et al.
Publicado: (2020)

Direct detection of alpha synuclein oligomers in vivo
por: Dimant, Hemi, et al.
Publicado: (2013)

The Bcl-2-associated athanogene gene family in tobacco (Nicotiana tabacum) and the function of NtBAG5 in leaf senescence
por: Gu, Linxin, et al.
Publicado: (2023)

Corrigendum: The Bcl-2-associated athanogene gene family in tobacco (Nicotiana tabacum) and the function of NtBAG5 in leaf senescence
por: Gu, Linxin, et al.
Publicado: (2023)

The Divergent Roles of the Rice bcl-2 Associated Athanogene (BAG) Genes in Plant Development and Environmental Responses
por: Zhou, Hailian, et al.
Publicado: (2021)

LRRK2 and α-Synuclein: Distinct or Synergistic Players in Parkinson’s Disease?
por: O’Hara, Darren M., et al.
Publicado: (2020)

Unraveling the role of tomato Bcl-2-associated athanogene (BAG) proteins during abiotic stress response and fruit ripening
por: Irfan, Mohammad, et al.
Publicado: (2021)

Genome-Wide Identification of the Bcl-2 Associated Athanogene (BAG) Gene Family in Solanum lycopersicum and the Functional Role of SlBAG9 in Response to Osmotic Stress
por: Jiang, Hailong, et al.
Publicado: (2022)

A Bcl-2 Associated Athanogene (bagA) Modulates Sexual Development and Secondary Metabolism in the Filamentous Fungus Aspergillus nidulans
por: Jain, Sachin, et al.
Publicado: (2018)

Bcl-2-associated athanogene 3(BAG3) is associated with tumor cell proliferation, migration, invasion and chemoresistance in colorectal cancer
por: Li, Ning, et al.
Publicado: (2018)

Bcl-2 Associated Athanogene 2 (BAG2) is Associated With Progression and Prognosis of Hepatocellular Carcinoma: A Bioinformatics-Based Analysis
por: Zhang, Xi, et al.
Publicado: (2021)

Author Correction: Unraveling the role of tomato Bcl-2-associated athanogene (BAG) proteins during abiotic stress response and fruit ripening
por: Irfan, Mohammad, et al.
Publicado: (2022)

Genome-wide in silico characterization and stress induced expression analysis of BcL-2 associated athanogene (BAG) family in Musa spp.
por: Dash, Ashutosh, et al.
Publicado: (2022)

The C. elegans UNC-23 protein, a member of the BCL-2-associated athanogene (BAG) family of chaperone regulators, interacts with HSP-1 to regulate cell attachment and maintain hypodermal integrity
por: Rahmani, Poupak, et al.
Publicado: (2015)

Early-onset impairment of the ubiquitin-proteasome system in dopaminergic neurons caused by α-synuclein
por: McKinnon, Chris, et al.
Publicado: (2020)

Generation of two human iPSC lines with Exon 3 mutations in BCL2-Associated Athanogene 3 (BAG3) from dilated cardiomyopathy patients
por: Zushin, Peter-James H., et al.
Publicado: (2023)

A plant Bcl-2-associated athanogene is proteolytically activated to confer fungal resistance
por: Kabbage, Mehdi, et al.
Publicado: (2016)

Bcl-2 associated athanogene 4 promotes proliferation, migration and invasion of gastric cancer cells
por: Yi, Lizhi, et al.
Publicado: (2017)

Therapeutic induction of Bcl2‐associated athanogene 3‐mediated autophagy in idiopathic pulmonary fibrosis
por: Chillappagari, Shashipavan, et al.
Publicado: (2022)

BCL2‐associated athanogene 6 exon24 contributes to testosterone synthesis and male fertility in mammals
por: Song, Huibin, et al.
Publicado: (2022)

Lung neuroendocrine tumors: correlation of ubiquitinylation and sumoylation with nucleo-cytosolic partitioning of PTEN
por: Collaud, Stéphane, et al.
Publicado: (2015)

Structure of the chromatin remodelling enzyme Chd1 bound to a ubiquitinylated nucleosome
por: Sundaramoorthy, Ramasubramanian, et al.
Publicado: (2018)

Role of BCL2-associated athanogene in resistance to platinum-based chemotherapy in non-small-cell lung cancer
por: WANG, YADI, et al.
Publicado: (2016)

Role of Bcl2-associated Athanogene 3 in Turnover of Gap Junction Protein, Connexin 43, in Neonatal Cardiomyocytes
por: Ghasemi Tahrir, Farzaneh, et al.
Publicado: (2019)

Rab5(Q79L) interacts with the carboxyl terminus of RUFY3
por: Yoshida, Hitomi, et al.
Publicado: (2010)

Chaperone-Based Therapies for Disease Modification in Parkinson's Disease
por: Friesen, Erik L., et al.
Publicado: (2017)

Predictors of Future Deep Brain Stimulation Surgery in de novo Parkinson's Disease
por: Lang, Stefan, et al.
Publicado: (2023)

Merging DBS with viral vector or stem cell implantation: “hybrid” stereotactic surgery as an evolution in the surgical treatment of Parkinson’s disease
por: Rowland, Nathan C, et al.
Publicado: (2016)

Disrupting the α-synuclein-ESCRT interaction with a peptide inhibitor mitigates neurodegeneration in preclinical models of Parkinson’s disease
por: Nim, Satra, et al.
Publicado: (2023)

Clustering and Negative Feedback by Endocytosis in Planar Cell Polarity Signaling Is Modulated by Ubiquitinylation of Prickle
por: Cho, Bomsoo, et al.
Publicado: (2015)

Expression of carboxyl terminus of Hsp70-interacting protein (CHIP) indicates poor prognosis in human gallbladder carcinoma
por: LIANG, ZHE LONG, et al.
Publicado: (2013)

Structure of a BAG6 (Bcl-2-associated Athanogene 6)-Ubl4a (Ubiquitin-like Protein 4a) Complex Reveals a Novel Binding Interface That Functions in Tail-anchored Protein Biogenesis
por: Kuwabara, Naoyuki, et al.
Publicado: (2015)

The De-Ubiquitinylating Enzyme, USP2, Is Associated with the Circadian Clockwork and Regulates Its Sensitivity to Light
por: Scoma, Heather Dehlin, et al.
Publicado: (2011)

Carboxyl Terminus of Hsp70-Interacting Protein Is Increased in Serum and Cerebrospinal Fluid of Patients With Spinocerebellar Ataxia Type 3
por: Hu, Zheng-wei, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_oum66nrkgqh2vbg44si698v8at