Cargando…

Phosphorylation of the MBF Repressor Yox1p by the DNA Replication Checkpoint Keeps the G1/S Cell-Cycle Transcriptional Program Active

BACKGROUND: In fission yeast Schizosaccharomyces pombe G1/S cell-cycle regulated transcription depends upon MBF. A negative feedback loop involving Nrm1p and Yox1p bound to MBF leads to transcriptional repression as cells exit G1 phase. However, activation of the DNA replication checkpoint response...

Descripción completa

Detalles Bibliográficos
Autores principales: Caetano, Catia, Klier, Steffi, de Bruin, Robertus A. M.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3040222/
https://www.ncbi.nlm.nih.gov/pubmed/21359180
http://dx.doi.org/10.1371/journal.pone.0017211