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Fate mapping of interleukin 17-producing T cells in inflammatory responses
We describe a reporter mouse strain designed to fate-map cells that have activated IL-17A. Here we show that T(H)17 cells show distinct plasticity in different inflammatory settings. Chronic inflammatory conditions in EAE caused a switch to alternative cytokines in T(H)17 cells, whereas acute cutane...
Autores principales: | Hirota, K., Duarte, J.H., Veldhoen, M., Hornsby, E., Li, Y., Cua, D.J., Ahlfors, H., Wilhelm, C., Tolaini, M., Menzel, U., Garefalaki, A., Potocnik, A.J., Stockinger, B |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3040235/ https://www.ncbi.nlm.nih.gov/pubmed/21278737 http://dx.doi.org/10.1038/ni.1993 |
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