Mast Cell/IL-4 Control of Francisella tularensis Replication and Host Cell Death is Associated with Increased ATP Production and Phagosomal Acidification

Mast cells are now recognized as effective modulators of innate immunity. We recently reported that mast cells and secreted interleukin-4 (IL-4) effectively control intramacrophage replication of Francisella tularensis Live Vaccine Strain (LVS), and that mice deficient in mast cells or IL-4 receptor...

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Detalles Bibliográficos
Autores principales: Rodriguez, Annette R., Yu, Jieh-Juen, Murthy, Ashlesh K., Guentzel, M. Neal, Klose, Karl E., Forsthuber, Thomas G., Chambers, James P., Berton, Michael T., Arulanandam, Bernard. P.
Formato: Texto
Lenguaje:English
Publicado: 2010
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3040285/
https://www.ncbi.nlm.nih.gov/pubmed/20861832
http://dx.doi.org/10.1038/mi.2010.59

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