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COX-2 Inhibition by Use of Rofecoxib or High Dose Aspirin Enhances ADP-Induced Platelet Aggregation in Fresh Blood

AIM: Increased cardiovascular risk after use of selective or nonselective cyclooxygenase-2 (COX-2)-inhibitors might partly be caused by enhanced platelet aggregability. However, an effect of COX-2 inhibition on platelets has so far not been observed in humans. METHODS: We tested in healthy volunteer...

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Detalles Bibliográficos
Autores principales:	Borgdorff, Piet, Handoko, M. Louis, Wong, Yeun Ying, Tangelder, Geert Jan
Formato:	Texto
Lenguaje:	English
Publicado:	Bentham Open 2010
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3040455/ https://www.ncbi.nlm.nih.gov/pubmed/21331307 http://dx.doi.org/10.2174/1874192401004010198

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