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Mapping of the Disease Locus and Identification of ADAMTS10 As a Candidate Gene in a Canine Model of Primary Open Angle Glaucoma
Primary open angle glaucoma (POAG) is a leading cause of blindness worldwide, with elevated intraocular pressure as an important risk factor. Increased resistance to outflow of aqueous humor through the trabecular meshwork causes elevated intraocular pressure, but the specific mechanisms are unknown...
Autores principales: | Kuchtey, John, Olson, Lana M., Rinkoski, Tommy, MacKay, Edward O., Iverson, T. M., Gelatt, Kirk N., Haines, Jonathan L., Kuchtey, Rachel W. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3040645/ https://www.ncbi.nlm.nih.gov/pubmed/21379321 http://dx.doi.org/10.1371/journal.pgen.1001306 |
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