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Prevalence of Epistasis in the Evolution of Influenza A Surface Proteins
The surface proteins of human influenza A viruses experience positive selection to escape both human immunity and, more recently, antiviral drug treatments. In bacteria and viruses, immune-escape and drug-resistant phenotypes often appear through a combination of several mutations that have epistati...
| Autores principales: | , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2011
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3040651/ https://www.ncbi.nlm.nih.gov/pubmed/21390205 http://dx.doi.org/10.1371/journal.pgen.1001301 |