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Innate Sensing of HIV-Infected Cells

Cell-free HIV-1 virions are poor stimulators of type I interferon (IFN) production. We examined here how HIV-infected cells are recognized by plasmacytoid dendritic cells (pDCs) and by other cells. We show that infected lymphocytes are more potent inducers of IFN than virions. There are target cell-...

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Detalles Bibliográficos
Autores principales:	Lepelley, Alice, Louis, Stéphanie, Sourisseau, Marion, Law, Helen K. W., Pothlichet, Julien, Schilte, Clémentine, Chaperot, Laurence, Plumas, Joël, Randall, Richard E., Si-Tahar, Mustapha, Mammano, Fabrizio, Albert, Matthew L., Schwartz, Olivier
Formato:	Texto
Lenguaje:	English
Publicado:	Public Library of Science 2011
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3040675/ https://www.ncbi.nlm.nih.gov/pubmed/21379343 http://dx.doi.org/10.1371/journal.ppat.1001284

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