The HDAC Inhibitor FK228 Enhances Adenoviral Transgene Expression by a Transduction-Independent Mechanism but Does Not Increase Adenovirus Replication

The histone deacetylase inhibitor FK228 has previously been shown to enhance adenoviral transgene expression when cells are pre-incubated with the drug. Upregulation of the coxsackie adenovirus receptor (CAR), leading to increased viral transduction, has been proposed as the main mechanism. In the p...

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Detalles Bibliográficos
Autores principales: Danielsson, Angelika, Dzojic, Helena, Rashkova, Victoria, Cheng, Wing-Shing, Essand, Magnus
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3040751/
https://www.ncbi.nlm.nih.gov/pubmed/21379379
http://dx.doi.org/10.1371/journal.pone.0014700

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3040751/
https://www.ncbi.nlm.nih.gov/pubmed/21379379
http://dx.doi.org/10.1371/journal.pone.0014700

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