Functional Characterization of Human Cancer-Derived TRKB Mutations

Cancer originates from cells that have acquired mutations in genes critical for controlling cell proliferation, survival and differentiation. Often, tumors continue to depend on these so-called driver mutations, providing the rationale for targeted anticancer therapies. To date, large-scale sequenci...

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Detalles Bibliográficos
Autores principales: Geiger, Thomas R., Song, Ji-Ying, Rosado, Aranzazu, Peeper, Daniel S.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3040757/
https://www.ncbi.nlm.nih.gov/pubmed/21379385
http://dx.doi.org/10.1371/journal.pone.0016871

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3040757/
https://www.ncbi.nlm.nih.gov/pubmed/21379385
http://dx.doi.org/10.1371/journal.pone.0016871

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