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Functional Characterization of Human Cancer-Derived TRKB Mutations
Cancer originates from cells that have acquired mutations in genes critical for controlling cell proliferation, survival and differentiation. Often, tumors continue to depend on these so-called driver mutations, providing the rationale for targeted anticancer therapies. To date, large-scale sequenci...
| Autores principales: | , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2011
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3040757/ https://www.ncbi.nlm.nih.gov/pubmed/21379385 http://dx.doi.org/10.1371/journal.pone.0016871 |