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HmuY Haemophore and Gingipain Proteases Constitute a Unique Syntrophic System of Haem Acquisition by Porphyromonas gingivalis
Haem (iron protoporphyrin IX) is both an essential growth factor and virulence regulator for the periodontal pathogen Porphyromonas gingivalis, which acquires it mainly from haemoglobin via the sequential actions of the R- and K-specific gingipain proteases. The haem-binding lipoprotein haemophore H...
Autores principales: | Smalley, John W., Byrne, Dominic P., Birss, Andrew J., Wojtowicz, Halina, Sroka, Aneta, Potempa, Jan, Olczak, Teresa |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3040768/ https://www.ncbi.nlm.nih.gov/pubmed/21390208 http://dx.doi.org/10.1371/journal.pone.0017182 |
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