Cargando…

HmuY Haemophore and Gingipain Proteases Constitute a Unique Syntrophic System of Haem Acquisition by Porphyromonas gingivalis

Haem (iron protoporphyrin IX) is both an essential growth factor and virulence regulator for the periodontal pathogen Porphyromonas gingivalis, which acquires it mainly from haemoglobin via the sequential actions of the R- and K-specific gingipain proteases. The haem-binding lipoprotein haemophore H...

Descripción completa

Detalles Bibliográficos
Autores principales:	Smalley, John W., Byrne, Dominic P., Birss, Andrew J., Wojtowicz, Halina, Sroka, Aneta, Potempa, Jan, Olczak, Teresa
Formato:	Texto
Lenguaje:	English
Publicado:	Public Library of Science 2011
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3040768/ https://www.ncbi.nlm.nih.gov/pubmed/21390208 http://dx.doi.org/10.1371/journal.pone.0017182

Ejemplares similares

Correction: HmuY Haemophore and Gingipain Proteases Constitute a Unique Syntrophic System of Haem Acquisition by Porphyromonas gingivalis
por: Smalley, John W., et al.
Publicado: (2011)

Correction: HmuY Haemophore and Gingipain Proteases Constitute a Unique Syntrophic System of Haem Acquisition by Porphyromonas gingivalis
por: Smalley, John W., et al.
Publicado: (2011)

Unique Structure and Stability of HmuY, a Novel Heme-Binding Protein of Porphyromonas gingivalis
por: Wójtowicz, Halina, et al.
Publicado: (2009)

Anti-HmuY Antibodies Specifically Recognize Porphyromonas gingivalis HmuY Protein but Not Homologous Proteins in Other Periodontopathogens
por: Śmiga, Michał, et al.
Publicado: (2015)

Differential roles of tryptophan residues in conformational stability of Porphyromonas gingivalis HmuY hemophore
por: Bielecki, Marcin, et al.
Publicado: (2014)

The Unique hmuY Gene Sequence as a Specific Marker of Porphyromonas gingivalis
por: Gmiterek, Anna, et al.
Publicado: (2013)

Species specificity, surface exposure, protein expression, immunogenicity, and participation in biofilm formation of Porphyromonas gingivalis HmuY
por: Olczak, Teresa, et al.
Publicado: (2010)

Role of Porphyromonas gingivalis HmuY in Immunopathogenesis of Chronic Periodontitis
por: Carvalho-Filho, P. C., et al.
Publicado: (2016)

Apoptosis Transcriptional Profile Induced by Porphyromonas gingivalis HmuY
por: Carvalho-Filho, Paulo C., et al.
Publicado: (2019)

Porphyromonas gingivalis HmuY and Streptococcus gordonii GAPDH—Novel Heme Acquisition Strategy in the Oral Microbiome
por: Ślęzak, Paulina, et al.
Publicado: (2020)

Interplay between Porphyromonas gingivalis Hemophore-Like Protein HmuY and Kgp/RgpA Gingipains Plays a Superior Role in Heme Supply
por: Śmiga, Michał, et al.
Publicado: (2023)

Tannerella forsythia Tfo belongs to Porphyromonas gingivalis HmuY-like family of proteins but differs in heme-binding properties
por: Bielecki, Marcin, et al.
Publicado: (2018)

Porphyromonas gingivalis HmuY and Bacteroides vulgatus Bvu—A Novel Competitive Heme Acquisition Strategy
por: Siemińska, Klaudia, et al.
Publicado: (2021)

Porphyromonas gingivalis HmuY stimulates expression of Bcl-2 and Fas by human CD3(+) T cells
por: Carvalho-Filho, Paulo C, et al.
Publicado: (2013)

Unique Properties of Heme Binding of the Porphyromonas gingivalis HmuY Hemophore-like Protein Result from the Evolutionary Adaptation of the Protein Structure
por: Kosno, Joanna, et al.
Publicado: (2022)

Pyocycanin, a Contributory Factor in Haem Acquisition and Virulence Enhancement of Porphyromonas gingivalis in the Lung
por: Benedyk, Malgorzata, et al.
Publicado: (2015)

Correction: Pyocycanin, a Contributory Factor in Haem Acquisition and Virulence Enhancement of Porphyromonas gingivalis in the Lung
por: Benedyk, Malgorzata, et al.
Publicado: (2016)

Lipoprotein modifications by gingipains of Porphyromonas gingivalis
por: Lönn, J., et al.
Publicado: (2018)

Structural properties of a haemophore facilitate targeted elimination of the pathogen Porphyromonas gingivalis
por: Gao, Jin-Long, et al.
Publicado: (2018)

Proteolytic Activity-Independent Activation of the Immune Response by Gingipains from Porphyromonas gingivalis
por: Ciaston, Izabela, et al.
Publicado: (2022)

Role of Porphyromonas gingivalis gingipains in multi-species biofilm formation
por: Bao, Kai, et al.
Publicado: (2014)

Porphyromonas gingivalis induce apoptosis in human gingival epithelial cells through a gingipain-dependent mechanism
por: Stathopoulou, Panagiota G, et al.
Publicado: (2009)

Structural determinants of inhibition of Porphyromonas gingivalis gingipain K by KYT-36, a potent, selective, and bioavailable peptidase inhibitor
por: Guevara, Tibisay, et al.
Publicado: (2019)

Exopeptidases and gingipains in Porphyromonas gingivalis as prerequisites for its amino acid metabolism
por: Nemoto, Takayuki K., et al.
Publicado: (2016)

regT can modulate gingipain activity and response to oxidative stress in Porphyromonas gingivalis
por: Vanterpool, E., et al.
Publicado: (2010)

In Porphyromonas gingivalis VimF Is Involved in Gingipain Maturation through the Transfer of Galactose
por: Muthiah, Arun S., et al.
Publicado: (2013)

Identification and Modification of Porphyromonas gingivalis Cysteine Protease, Gingipain, Ideal for Screening Periodontitis
por: Hirai, Kimito, et al.
Publicado: (2020)

Molecular docking analysis of imidazole quinolines with gingipain R from Porphyromonas gingivalis
por: Reddy, Kanumuru Rahul, et al.
Publicado: (2023)

Distinct roles of long/short fimbriae and gingipains in homotypic biofilm development by Porphyromonas gingivalis
por: Kuboniwa, Masae, et al.
Publicado: (2009)

Porphyromonas gingivalis Regulates TREM-1 in Human Polymorphonuclear Neutrophils via Its Gingipains
por: Bostanci, Nagihan, et al.
Publicado: (2013)

Correction: In Porphyromonas gingivalis VimF Is Involved in Gingipain Maturation through the Transfer of Galactose
por: Muthiah, Arun S., et al.
Publicado: (2019)

Implications of Porphyromonas gingivalis peptidyl arginine deiminase and gingipain R in human health and diseases
por: Chow, Yoke Chan, et al.
Publicado: (2022)

Proteolysis of Gingival Keratinocyte Cell Surface Proteins by Gingipains Secreted From Porphyromonas gingivalis – Proteomic Insights Into Mechanisms Behind Tissue Damage in the Diseased Gingiva
por: Hočevar, Katarina, et al.
Publicado: (2020)

Porphyromonas gingivalis Gingipains-Mediated Degradation of Plasminogen Activator Inhibitor-1 Leads to Delayed Wound Healing Responses in Human Endothelial Cells
por: Song, Li-Ting, et al.
Publicado: (2021)

Transcriptional profiling of human smooth muscle cells infected with gingipain and fimbriae mutants of Porphyromonas gingivalis
por: Zhang, Boxi, et al.
Publicado: (2016)

Porphyromonas gingivalis Gingipain-Dependently Enhances IL-33 Production in Human Gingival Epithelial Cells
por: Tada, Hiroyuki, et al.
Publicado: (2016)

Alzheimer’s Disease-Like Neurodegeneration in Porphyromonas gingivalis Infected Neurons with Persistent Expression of Active Gingipains
por: Haditsch, Ursula, et al.
Publicado: (2020)

Quantum curcumin mediated inhibition of gingipains and mixed-biofilm of Porphyromonas gingivalis causing chronic periodontitis
por: Singh, Ashish Kumar, et al.
Publicado: (2018)

Porphyromonas gingivalis laboratory strains and clinical isolates exhibit different distribution of cell surface and secreted gingipains
por: Seers, Christine A., et al.
Publicado: (2020)

Correction: Quantum curcumin mediated inhibition of gingipains and mixed-biofilm of Porphyromonas gingivalis causing chronic periodontitis
por: Singh, Ashish Kumar, et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_e20jfkehja9foe0mdv6o2p0cvk