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HmuY Haemophore and Gingipain Proteases Constitute a Unique Syntrophic System of Haem Acquisition by Porphyromonas gingivalis

Haem (iron protoporphyrin IX) is both an essential growth factor and virulence regulator for the periodontal pathogen Porphyromonas gingivalis, which acquires it mainly from haemoglobin via the sequential actions of the R- and K-specific gingipain proteases. The haem-binding lipoprotein haemophore H...

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Detalles Bibliográficos
Autores principales: Smalley, John W., Byrne, Dominic P., Birss, Andrew J., Wojtowicz, Halina, Sroka, Aneta, Potempa, Jan, Olczak, Teresa
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3040768/
https://www.ncbi.nlm.nih.gov/pubmed/21390208
http://dx.doi.org/10.1371/journal.pone.0017182

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