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Genetic Evidence for Involvement of Neuronally Expressed S1P(1) Receptor in Nociceptor Sensitization and Inflammatory Pain
Sphingosine-1-phosphate (S1P) is a key regulator of immune response. Immune cells, epithelia and blood cells generate high levels of S1P in inflamed tissue. However, it is not known if S1P acts on the endings of nociceptive neurons, thereby contributing to the generation of inflammatory pain. We fou...
| Autores principales: | , , , , , , , , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2011
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3040773/ https://www.ncbi.nlm.nih.gov/pubmed/21359147 http://dx.doi.org/10.1371/journal.pone.0017268 |