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Elevated O-GlcNAc-dependent signaling through inducible mOGT expression selectively triggers apoptosis
O-linked N-acetylglucosamine transferase (OGT) catalyzes O-GlcNAc addition to numerous cellular proteins including transcription and nuclear pore complexes and plays a key role in cellular signaling. One differentially spliced isoform of OGT is normally targeted to mitochondria (mOGT) but is quite c...
| Autores principales: | , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Springer Vienna
2010
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3040817/ https://www.ncbi.nlm.nih.gov/pubmed/20824293 http://dx.doi.org/10.1007/s00726-010-0719-8 |