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Antifungal Activity of Plant Extracts against Candida Species from Oral Lesions

Seventy five patients with oral lesions attending the different departments of Rajah Muthiah Medical College and Hospital, Annamalai University were screened for Candida. Forty six (61.3%) Candida strains were isolated from the oral lesions. Of the 46 Candida strains, Candida albicans accounted for...

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Autores principales: Prabhakar, K., Kumar, L. Sathish, Rajendran, S., Chandrasekaran, M., Bhaskar, K., Sajit Khan, A. K.
Formato: Texto
Lenguaje:English
Publicado: Medknow Publications 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3040880/
https://www.ncbi.nlm.nih.gov/pubmed/21369447
http://dx.doi.org/10.4103/0250-474X.49128
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author Prabhakar, K.
Kumar, L. Sathish
Rajendran, S.
Chandrasekaran, M.
Bhaskar, K.
Sajit Khan, A. K.
author_facet Prabhakar, K.
Kumar, L. Sathish
Rajendran, S.
Chandrasekaran, M.
Bhaskar, K.
Sajit Khan, A. K.
author_sort Prabhakar, K.
collection PubMed
description Seventy five patients with oral lesions attending the different departments of Rajah Muthiah Medical College and Hospital, Annamalai University were screened for Candida. Forty six (61.3%) Candida strains were isolated from the oral lesions. Of the 46 Candida strains, Candida albicans accounted for 35 (76.08%), Candida glabrata for 5 (10.86%), Candida tropicalis and Candida krusei for 2 (4.34%) each and Candida parapsilosis and Candida guilliermondii for one (2.17%) each. Antifungal activity of ethanol extracts of five plant species that included Syzygium jambolanum, Cassia siamea, Odina wodier, Momordica charantia and Melia azedarach and two algal species, Sargassum wightii and Caulerpa scalpelliformis were tested against 25 isolated strains by disc diffusion method. Antifungal activity was observed at 100 mg/ml for Syzygium jambolanum, Cassia siamea and Caulerpa scalpelliformis and at 10 mg/ml for Sargassum wightii.
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spelling pubmed-30408802011-03-02 Antifungal Activity of Plant Extracts against Candida Species from Oral Lesions Prabhakar, K. Kumar, L. Sathish Rajendran, S. Chandrasekaran, M. Bhaskar, K. Sajit Khan, A. K. Indian J Pharm Sci Short Communication Seventy five patients with oral lesions attending the different departments of Rajah Muthiah Medical College and Hospital, Annamalai University were screened for Candida. Forty six (61.3%) Candida strains were isolated from the oral lesions. Of the 46 Candida strains, Candida albicans accounted for 35 (76.08%), Candida glabrata for 5 (10.86%), Candida tropicalis and Candida krusei for 2 (4.34%) each and Candida parapsilosis and Candida guilliermondii for one (2.17%) each. Antifungal activity of ethanol extracts of five plant species that included Syzygium jambolanum, Cassia siamea, Odina wodier, Momordica charantia and Melia azedarach and two algal species, Sargassum wightii and Caulerpa scalpelliformis were tested against 25 isolated strains by disc diffusion method. Antifungal activity was observed at 100 mg/ml for Syzygium jambolanum, Cassia siamea and Caulerpa scalpelliformis and at 10 mg/ml for Sargassum wightii. Medknow Publications 2008 /pmc/articles/PMC3040880/ /pubmed/21369447 http://dx.doi.org/10.4103/0250-474X.49128 Text en © Indian Journal of Pharmaceutical Sciences http://creativecommons.org/licenses/by/2.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Short Communication
Prabhakar, K.
Kumar, L. Sathish
Rajendran, S.
Chandrasekaran, M.
Bhaskar, K.
Sajit Khan, A. K.
Antifungal Activity of Plant Extracts against Candida Species from Oral Lesions
title Antifungal Activity of Plant Extracts against Candida Species from Oral Lesions
title_full Antifungal Activity of Plant Extracts against Candida Species from Oral Lesions
title_fullStr Antifungal Activity of Plant Extracts against Candida Species from Oral Lesions
title_full_unstemmed Antifungal Activity of Plant Extracts against Candida Species from Oral Lesions
title_short Antifungal Activity of Plant Extracts against Candida Species from Oral Lesions
title_sort antifungal activity of plant extracts against candida species from oral lesions
topic Short Communication
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3040880/
https://www.ncbi.nlm.nih.gov/pubmed/21369447
http://dx.doi.org/10.4103/0250-474X.49128
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