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Spectrophotometric Estimation of Bicalutamide in Tablets
A simple, sensitive, rapid, accurate and precise spectrophotometric method has been developed for the estimation of bicalutamide in bulk and pharmaceutical dosage forms. Bicalutamide shows maximum absorbance at 272 nm with molar absorptivity of 2.3399×10(4) l/mol/cm. Beer's law was obeyed in th...
| Autores principales: | , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Medknow Publications
2008
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3040883/ https://www.ncbi.nlm.nih.gov/pubmed/21369450 http://dx.doi.org/10.4103/0250-474X.49131 |
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| author | Sancheti, P. P. Vyas, V. M. Shah, Manali Karekar, Poonam Pore, Y. V. |
| author_facet | Sancheti, P. P. Vyas, V. M. Shah, Manali Karekar, Poonam Pore, Y. V. |
| author_sort | Sancheti, P. P. |
| collection | PubMed |
| description | A simple, sensitive, rapid, accurate and precise spectrophotometric method has been developed for the estimation of bicalutamide in bulk and pharmaceutical dosage forms. Bicalutamide shows maximum absorbance at 272 nm with molar absorptivity of 2.3399×10(4) l/mol/cm. Beer's law was obeyed in the concentration range of 1.5-18 μg/ml. The limit of detection and limit of quantification were found to be 0.1 and 0.4 μg/ml, respectively. Results of analysis were validated statistically and by recovery studies. |
| format | Text |
| id | pubmed-3040883 |
| institution | National Center for Biotechnology Information |
| language | English |
| publishDate | 2008 |
| publisher | Medknow Publications |
| record_format | MEDLINE/PubMed |
| spelling | pubmed-30408832011-03-02 Spectrophotometric Estimation of Bicalutamide in Tablets Sancheti, P. P. Vyas, V. M. Shah, Manali Karekar, Poonam Pore, Y. V. Indian J Pharm Sci Short Communication A simple, sensitive, rapid, accurate and precise spectrophotometric method has been developed for the estimation of bicalutamide in bulk and pharmaceutical dosage forms. Bicalutamide shows maximum absorbance at 272 nm with molar absorptivity of 2.3399×10(4) l/mol/cm. Beer's law was obeyed in the concentration range of 1.5-18 μg/ml. The limit of detection and limit of quantification were found to be 0.1 and 0.4 μg/ml, respectively. Results of analysis were validated statistically and by recovery studies. Medknow Publications 2008 /pmc/articles/PMC3040883/ /pubmed/21369450 http://dx.doi.org/10.4103/0250-474X.49131 Text en © Indian Journal of Pharmaceutical Sciences http://creativecommons.org/licenses/by/2.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
| spellingShingle | Short Communication Sancheti, P. P. Vyas, V. M. Shah, Manali Karekar, Poonam Pore, Y. V. Spectrophotometric Estimation of Bicalutamide in Tablets |
| title | Spectrophotometric Estimation of Bicalutamide in Tablets |
| title_full | Spectrophotometric Estimation of Bicalutamide in Tablets |
| title_fullStr | Spectrophotometric Estimation of Bicalutamide in Tablets |
| title_full_unstemmed | Spectrophotometric Estimation of Bicalutamide in Tablets |
| title_short | Spectrophotometric Estimation of Bicalutamide in Tablets |
| title_sort | spectrophotometric estimation of bicalutamide in tablets |
| topic | Short Communication |
| url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3040883/ https://www.ncbi.nlm.nih.gov/pubmed/21369450 http://dx.doi.org/10.4103/0250-474X.49131 |
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