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Shared Genomics: Developing an accessible integrated analysis platform for Genome-Wide Association Studies
Increasingly, genome-wide association studies are being used to identify positions within the human genome that have a link with a disease condition. The number of genomic locations studied means that computationally intensive and bioinformatic intensive solutions will have to be used in the analysi...
Autores principales: | , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
American Medical Informatics Association
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3041536/ https://www.ncbi.nlm.nih.gov/pubmed/21347139 |
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author | Hoyle, David Delderfield, Mark Kitching, Lee Smith, Gareth Buchan, Iain |
author_facet | Hoyle, David Delderfield, Mark Kitching, Lee Smith, Gareth Buchan, Iain |
author_sort | Hoyle, David |
collection | PubMed |
description | Increasingly, genome-wide association studies are being used to identify positions within the human genome that have a link with a disease condition. The number of genomic locations studied means that computationally intensive and bioinformatic intensive solutions will have to be used in the analysis of these data sets. In this paper we present an integrated Workbench that provides user-friendly access to parallelized statistical genetics analysis codes for clinical researchers. In addition we biologically annotate statistical analysis results through the reuse of existing bionformatic Taverna workflows. |
format | Text |
id | pubmed-3041536 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2010 |
publisher | American Medical Informatics Association |
record_format | MEDLINE/PubMed |
spelling | pubmed-30415362011-02-23 Shared Genomics: Developing an accessible integrated analysis platform for Genome-Wide Association Studies Hoyle, David Delderfield, Mark Kitching, Lee Smith, Gareth Buchan, Iain Summit on Translat Bioinforma Articles Increasingly, genome-wide association studies are being used to identify positions within the human genome that have a link with a disease condition. The number of genomic locations studied means that computationally intensive and bioinformatic intensive solutions will have to be used in the analysis of these data sets. In this paper we present an integrated Workbench that provides user-friendly access to parallelized statistical genetics analysis codes for clinical researchers. In addition we biologically annotate statistical analysis results through the reuse of existing bionformatic Taverna workflows. American Medical Informatics Association 2010-03-01 /pmc/articles/PMC3041536/ /pubmed/21347139 Text en ©2010 AMIA - All rights reserved. This is an Open Access article: verbatim copying and redistribution of this article are permitted in all media for any purpose |
spellingShingle | Articles Hoyle, David Delderfield, Mark Kitching, Lee Smith, Gareth Buchan, Iain Shared Genomics: Developing an accessible integrated analysis platform for Genome-Wide Association Studies |
title | Shared Genomics: Developing an accessible integrated analysis platform for Genome-Wide Association Studies |
title_full | Shared Genomics: Developing an accessible integrated analysis platform for Genome-Wide Association Studies |
title_fullStr | Shared Genomics: Developing an accessible integrated analysis platform for Genome-Wide Association Studies |
title_full_unstemmed | Shared Genomics: Developing an accessible integrated analysis platform for Genome-Wide Association Studies |
title_short | Shared Genomics: Developing an accessible integrated analysis platform for Genome-Wide Association Studies |
title_sort | shared genomics: developing an accessible integrated analysis platform for genome-wide association studies |
topic | Articles |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3041536/ https://www.ncbi.nlm.nih.gov/pubmed/21347139 |
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